Ophth - Carb

(Carbachol 0.01%)
Sterile Intraocular Solution

Carbachol is one of the main agents used in procedures such as cataract extraction to produce instant miosis. Also helps in keeping the filtration angle open, securing intraocular lens in posterior chamber or in bag. It also keeps iris away from corneal wound thus avoids incarceration of iris in the wound.

It is a parasympathomimetic agent with the muscarinic and nicotinic actions of acetylcholine, having prolonged actions than those of acetylcholine.


Ophth-Carb is a PRESERVATIVE FREE. Sterile solution of carbachol (0.01%) for intraocular use; Each ml contains. Active: Carbachol 0.1 mg. Inactives: Sodium chloride, Potassium chloride, Calcium chloride dihydrate, Magnesium chloride hexahydrate, Sodium acetate trihydrate, Sodium citrate dihydrate, Sodium hydroxide and/or hydrochloric acid (to adjust pH) and Water for Injection..


Carbachol is a potent cholinergic (parasynpathomimitic) agent.


Ophth-Carb (Carbachol 0.01%) is used intraocularly to produce miosis during surgery.


The use of Ophth-Carb is contraindicated in those patients showing hypersensitivity to any of the components of this preparation.


Intraocular carbachol 0.01% should be used with caution in patients with acute cardiac failure, bronchial asthma, peptic ulcer, hyperthyroidism, gastorintestinal spasm, urinary tract obstruction and Parkinson's disease.

Adverse reactions/Side Effects

Effects such as flushing sweating epigastric distress abdominal cramps, tightness in urinary bladder, and headache have been reported after systemic or topical use of carbachol.

After cataract extraction with utilization of intraocular carbachol corneal clouding, persistent bullous keratopathy and iritis have been reported in a rare case. Retinal detachment has been reported when miotics are used in certain susceptible individuals.

Dosage and administration

NOT MORE THAN ONE-HALF MILLILITER. It is better to administer one or two drops into the anterior chamber for the production of satisfactory miosis. It is safer to dilute Carbachol 0.01% intraocular solution with equal quantity of BSS or Ringer's solution. Miosis is usually maximal within two to five minutes after application.


It is safer to use carbachol solution diluted with equal quantity of Balanced Salt Solution (BSS) or Ringer's solution. Afterwards thoroughly wash anterior chamber with BSS or Ringer's solution.


Ophth-Carb should be stored at a temperature below 30°C. Protect from freezing.

How supplied

Ophth-Carb is supplied as 1.5 ml sterile solution contained in a sterile vial along-with a sterile disposable syringe.


Sterility lost once opened or damaged.
For intraocular use only
Not for parenteral or oral use.
Keep away from the reach of children.

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